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Insights into dosimetry and the investigation of dose effects in molecular radiotherapy (MRT)

Insights into dosimetry and the investigation of dose effects in molecular radiotherapy (MRT)

Molecular radiotherapy (MRT) is a rapidly growing field of minimally invasive cancer treatment in nuclear medicine. In recent years, its application, especially in prostate cancer therapy, has expanded significantly. However, depending on the type of MRT, our understanding of dose effects on tumors and organs at risk remains limited, preventing further optimization of treatments through personalized dosing.

Personalized dosimetry has the potential to tailor treatments to individual patients, maximizing therapeutic efficacy while minimizing side effects. Therefore, this research topic aims to bring together the latest research on personalized dosimetry and dose-effect relationships from both clinical and fundamental studies. By focusing on these areas, we hope to advance the development of dosimetry methods and improve the efficacy of MRT through individualized treatment approaches, contributing to the continued evolution of precision medicine in radionuclide therapy.

In this research topic, we aim to present the latest research advances in MRT. Our focus is on highlighting progress in evaluating dose-effect relationships, a key factor in optimizing treatment outcomes. By bringing together studies from across the field, we hope to provide insights into how various factors influence the therapeutic effects of MRT at different doses. In addition, we aim to highlight innovative approaches to personalized dosimetry, a rapidly growing field of research.

This research topic accepts all article types within the scope of the topic.


Key words: Radionuclide therapy, Radiopeptide therapy, Dosimetry, Personalized dosing, Dose-effect relationship, Time-activity curve, Response to therapy, MRT


Important note: All contributions to this research topic must fall within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to refer an out-of-scope manuscript to a more appropriate section or journal at any stage of peer review.

Molecular radiotherapy (MRT) is a rapidly growing field of minimally invasive cancer treatment in nuclear medicine. In recent years, its application, especially in prostate cancer therapy, has expanded significantly. However, depending on the type of MRT, our understanding of dose effects on tumors and organs at risk remains limited, preventing further optimization of treatments through personalized dosing.

Personalized dosimetry has the potential to tailor treatments to individual patients, maximizing therapeutic efficacy while minimizing side effects. Therefore, this research topic aims to bring together the latest research on personalized dosimetry and dose-effect relationships from both clinical and fundamental studies. By focusing on these areas, we hope to advance the development of dosimetry methods and improve the efficacy of MRT through individualized treatment approaches, contributing to the continued evolution of precision medicine in radionuclide therapy.

In this research topic, we aim to present the latest research advances in MRT. Our focus is on highlighting progress in evaluating dose-effect relationships, a key factor in optimizing treatment outcomes. By bringing together studies from across the field, we hope to provide insights into how various factors influence the therapeutic effects of MRT at different doses. In addition, we aim to highlight innovative approaches to personalized dosimetry, a rapidly growing field of research.

This research topic accepts all article types within the scope of the topic.


Key words: Radionuclide therapy, Radiopeptide therapy, Dosimetry, Personalized dosing, Dose-effect relationship, Time-activity curve, Response to therapy, MRT


Important note: All contributions to this research topic must fall within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to refer an out-of-scope manuscript to a more appropriate section or journal at any stage of peer review.